A joint modeling approach for uncovering associations between gene expression, bioactivity and chemical structure in early drug discovery to guide lead selection and genomic biomarker development

JOURNAL ARTICLE published 1 August 2016 in Statistical Applications in Genetics and Molecular Biology

Authors: Nolen Perualila-Tan | Adetayo Kasim | Willem Talloen | Bie Verbist | Hinrich W.H. Göhlmann | Ziv Shkedy

Approximate Bayesian computation with functional statistics

JOURNAL ARTICLE published 26 January 2013 in Statistical Applications in Genetics and Molecular Biology

Authors: Samuel Soubeyrand | Florence Carpentier | François Guiton | Etienne K. Klein

Incorporating Duplicate Genotype Data into Linear Trend Tests of Genetic Association: Methods and Cost-Effectiveness

JOURNAL ARTICLE published 5 January 2009 in Statistical Applications in Genetics and Molecular Biology

Authors: Bryce Borchers | Marshall Brown | Brian McLellan | Airat Bekmetjev | Nathan L Tintle

Testing for Gene-Gene Interaction with AMMI Models

JOURNAL ARTICLE published 6 January 2010 in Statistical Applications in Genetics and Molecular Biology

Authors: Amina Barhdadi | Marie-Pierre Dubé

Supervised Detection of Regulatory Motifs in DNA Sequences

JOURNAL ARTICLE published 25 January 2003 in Statistical Applications in Genetics and Molecular Biology

Authors: Sunduz Keles | Mark J. van der Laan | Sandrine Dudoit | Biao Xing | Michael B. Eisen

Empirical Bayes Microarray ANOVA and Grouping Cell Lines by Equal Expression Levels

JOURNAL ARTICLE published 18 January 2005 in Statistical Applications in Genetics and Molecular Biology

Authors: Ingrid Lönnstedt | Rebecca Rimini | Peter Nilsson

A Bayesian mixture model for chromatin interaction data

JOURNAL ARTICLE published 1 January 2015 in Statistical Applications in Genetics and Molecular Biology

Authors: Liang Niu | Shili Lin

Lasso Logistic Regression, GSoft and the Cyclic Coordinate Descent Algorithm: Application to Gene Expression Data

JOURNAL ARTICLE published 12 January 2010 in Statistical Applications in Genetics and Molecular Biology

Authors: Manuel Garcia-Magariños | Anestis Antoniadis | Ricardo Cao | Wenceslao González-Manteiga

FC1000: normalized gene expression changes of systematically perturbed human cells

JOURNAL ARTICLE published 26 January 2017 in Statistical Applications in Genetics and Molecular Biology

Authors: Ingrid M. Lönnstedt | Sven Nelander

EBADIMEX: an empirical Bayes approach to detect joint differential expression and methylation and to classify samples

JOURNAL ARTICLE published 18 December 2019 in Statistical Applications in Genetics and Molecular Biology

Research funded by Independent Research Fund Denmark (7016-00379) | Sapere Aude (12-126439) | Innovation Fund Denmark (10-092320/DSF)

Authors: Tobias Madsen | Michał Świtnicki | Malene Juul | Jakob Skou Pedersen

Empirical likelihood tests for nonparametric detection of differential expression from RNA-seq data

JOURNAL ARTICLE published 1 January 2015 in Statistical Applications in Genetics and Molecular Biology

Authors: Thomas Thorne

On an extended interpretation of linkage disequilibrium in genetic case-control association studies

JOURNAL ARTICLE published 1 January 2015 in Statistical Applications in Genetics and Molecular Biology

Authors: Thorsten Dickhaus | Jens Stange | Haydar Demirhan

Predicting Protein Concentrations with ELISA Microarray Assays, Monotonic Splines and Monte Carlo Simulation

JOURNAL ARTICLE published 14 January 2008 in Statistical Applications in Genetics and Molecular Biology

Authors: Don Simone Daly | Kevin K Anderson | Amanda M White | Rachel M Gonzalez | Susan M Varnum | Richard C Zangar

Multiple comparisons in genetic association studies: a hierarchical modeling approach

JOURNAL ARTICLE published 1 January 2014 in Statistical Applications in Genetics and Molecular Biology

Authors: Nengjun Yi | Shizhong Xu | Xiang-Yang Lou | Himel Mallick

Time Dependent ROC Curves for the Estimation of True Prognostic Capacity of Microarray Data

JOURNAL ARTICLE published 22 January 2012 in Statistical Applications in Genetics and Molecular Biology

Authors: Yohann Foucher | Richard Danger

FADO: A Statistical Method to Detect Favored or Avoided Distances between Occurrences of Motifs using the Hawkes' Model

JOURNAL ARTICLE published 12 January 2005 in Statistical Applications in Genetics and Molecular Biology

Authors: Gaelle Gusto | Sophie Schbath

Examining Protein Structure and Similarities by Spectral Analysis Technique

JOURNAL ARTICLE published 17 January 2006 in Statistical Applications in Genetics and Molecular Biology

Authors: Krista Collins | Hong Gu | Chris Field

Continuous Covariates in Genetic Association Studies of Case-Parent Triads: Gene and Gene-Environment Interaction Effects, Population Stratification, and Power Analysis

JOURNAL ARTICLE published 15 January 2005 in Statistical Applications in Genetics and Molecular Biology

Authors: Sooyeol Lim | Joseph Beyene | Celia M. T. Greenwood

Statistical Analysis of Adsorption Models for Oligonucleotide Microarrays

JOURNAL ARTICLE published 9 January 2004 in Statistical Applications in Genetics and Molecular Biology

Authors: Conrad J Burden | Yvonne E Pittelkow | Susan R Wilson

A hidden Markov-model for gene mapping based on whole-genome next generation sequencing data

JOURNAL ARTICLE published 1 January 2015 in Statistical Applications in Genetics and Molecular Biology

Authors: Jürgen Claesen | Tomasz Burzykowski